In Vitro Fertilization Center
Gender Selection
You choose your child's gender

What is Gender Selection?
Gender selection is a medical practice that provides the opportunity to consciously choose the gender of the child and is carried out through various assisted reproductive technologies. This application is performed during the IVF (in vitro fertilization) process together with Preimplantation Genetic Screening (PGT). Embryos develop in a laboratory environment for a few days after fertilization, and their gender and chromosome health are checked during this time. Healthy and desired gender embryos are transferred to the uterus. Gender selection is used to prevent some chromosomal anomalies, especially chromosomes 13, 18, 21, X and Y. This detects chromosome-related diseases such as Down Syndrome and Turner. Gender selection may also be preferred for family balance.
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Embryo Gender Selection Methods
PGT Gender Selection Method
PGT-A (Preimplantation Genetic Diagnosis) is a technology that is integrated into the in vitro fertilization (IVF) process and allows the chromosomes of embryos to be examined. This test is specifically known as PGT-A (Preimplantation Genetic Screening) and is used to detect chromosomal abnormalities in embryos. Gender selection is one of the applications of PGT technology and offers couples the opportunity to choose the gender of their unborn child in order to prevent certain chromosome-related diseases or to ensure gender balance within the family.
Gender selection with PGT is based on the process of taking a cell sample and using it for genetic analysis after fertilized embryos reach a certain developmental stage in the laboratory environment. During this analysis, chromosomes 13, 18, 21, X and Y of the embryos are examined, thus detecting male embryos (XY) and female embryos (XX) and healthy embryos without diseases related to these 5 chromosomes.
NGS Gender Selection Method
NGS (Next Generation Sequencing) is one of the modern genetic analysis technologies and when used in combination with Preimplantation Genetic Testing (PGT) during the IVF (in vitro fertilization) process, it allows examining the chromosomal and genetic structure of embryos in detail. NGS is used to create a complete profile of chromosomal material by amplifying a very small sample of DNA from embryos millions of times.
Thanks to NGS technology, the genetic structures of embryos are analyzed with very high resolution, which provides great accuracy in determining gender as well as chromosomal anomalies in the PGT-A (Preimplantation Genetic Screening) process. Gender selection may be preferred in order to prevent some chromosome-related diseases or by families who want to ensure gender balance within the family.

Benefits of PGT and NGS Methods
PGT (Preimplantation Genetic Testing) and NGS (Next Generation Sequencing) methods have revolutionized genetic screening during the in vitro fertilization (IVF) process and increased the chances of having children for many couples. Here are the main benefits of these two methods:
Detection of Genetic Diseases: PGT enables screening of embryos in terms of chromosome structure, so that chromosomal abnormalities are detected at an early stage. NGS, on the other hand, is a technology used during PGT procedures and allows the detection of all chromosome abnormalities by providing a more detailed examination of DNA.
Gender Selection: Both PGT and NGS offer couples the opportunity to choose gender. This may be especially preferred for the purpose of preventing sex-linked genetic diseases or when gender balance within the family is desired.
Higher Pregnancy and Live Birth Rates: Choosing healthy embryos with their chromosome structure increases the chance of pregnancy and the likelihood of resulting in a healthy pregnancy. Detailed analysis with NGS helps select the healthiest embryos, which significantly increases the success rate of IVF treatments.
Reducing the Risk of Miscarriage: Chromosomal abnormalities are a common cause of miscarriage. PGT and NGS help reduce the risk of miscarriage by avoiding the use of embryos with potential chromosomal problems.
Single Embryo Transfer (SET): SET is the process of transferring a single healthy embryo instead of transferring multiple embryos. Thanks to PGT and NGS, more information is gained about the genetic health of embryos, making single embryo transfer safer and more effective. This reduces the risks of multiple pregnancies and makes the pregnancy process safer.
Advanced genetic screening techniques such as PGT and NGS are groundbreaking innovations in reproductive medicine and have helped many couples make their dreams of having children come true, while ensuring healthier and safer pregnancies.

How Successful Are PGT-A and NGS Methods?
PGT (Preimplantation Genetic Diagnosis) and NGS (Next Generation Sequencing) methods are advanced genetic screening techniques used in IVF (in vitro fertilization) processes. While PGT is used specifically to detect chromosomal abnormalities, NGS allows DNA to be analyzed more comprehensively, allowing the entire chromosome structure of embryos to be examined in great detail.
These methods increase the chance of pregnancy by selecting healthy embryos and reduce the risk of transmitting diseases related to chromosomal anomalies. These techniques are especially recommended for couples who have experienced recurrent pregnancy losses or unsuccessful results from previous IVF attempts. The success of PGT and NGS, although providing highly accurate results, also depends on other variables such as embryo quality, patient age, and other treatment factors.
In general, the use of PGT and NGS in IVF treatment significantly increases live birth rates. However, the success of these methods is not guaranteed in every case and individual situations may vary. Both methods are best evaluated as part of a process guided by genetic counseling and reproductive health professionals.
Frequently asked Questions
What is Gender Selection and How is It Done?
Gender selection is carried out using PGT technology used during the IVF (in vitro fertilization) process. PGT is used to determine the sex and chromosome health of fertilized embryos. Gender selection is generally preferred to ensure gender balance in the family or to prevent gender-related genetic diseases. This method allows the sex of embryos to be determined before implantation.
Is Gender Selection Safe?
Cinsiyet seçimi, IVF ve PGT gibi modern üreme teknolojileri kullanılarak yapılabilmekte ve bu yöntemler yüksek doğruluk oranları sunmaktadır. Özellikle PGT-A ve NGS embriyoların cinsiyetini belirlemekte %99 üzerinde bir doğruluk oranı ile oldukça etkilidir. Bu süreçler, genellikle kromozom hastalıkların önlenmesi gibi tıbbi nedenlerle kullanılır ve birçok ülkede yasal düzenlemelere tabiidir
Is Gender Selection Legal in All Cases?
The legality of gender selection varies from country to country. In some countries, gender selection, especially for non-medical reasons, is prohibited or severely restricted. PGT and NGS methods are possible in Cyprus.
What is PGT and How Does It Work?
PGT is a test that allows screening of the chromosome structure of embryos during the IVF process. Chromosomal abnormalities are detected on cells taken from embryos. This method is used to increase the chances of healthy pregnancy.
What is the difference between PGT and NGS?
NGS is a more advanced chromosome or genetic analysis technology using PGT. While PGT evaluates the most common 5 chromosome anomalies of embryos, NGS can perform more detailed analyzes and detect more specific genetic conditions such as single gene diseases and chromosomal translocations.
Who are PGT and NGS suitable for?
It is generally recommended for individuals over the age of 35, those who have experienced recurrent pregnancy losses, or those at risk of genetic diseases. These tests may also be recommended for those who have had unsuccessful IVF attempts despite quality embryos. It is also used for gender selection.
What is the Cost of Using PGT and NGS?
The cost of PGT and NGS tests varies depending on the scope of the test. These tests are often costly, but can reduce costs in the long run by increasing the chances of success with in vitro fertilization.
